(박사)서울대학교 약학대학 약학과

· 서울대학교 약학박사 (약물동태학 전공)

· 서울대학교 종합약학연구소 박사후연구원

· 종근당 종합연구소 책임연구원

· 바이오코아 선임연구원

· C&C신약연구소 책임연구원 - 일본 Chugai제약 연구소 파견연구원

· 약물의 흡수, 분포, 대사 및 배설 (ADME) 연구

· PK/PD Modeling and Simulation 연구

· PBPK (Physiologically Based Pharmacokinetics) modeling 연구

· 약물동태학 (Pharmacokinetics)

· 약리학 (Pharmacology)

· 임상약학 (Clinical Pharmacology)

논문

1. E.S. Son, X. Fei, J.H. Yoon, S.Y. Seo, H.J. Maeng, S.H. Jeong, Y.C. Kim. Comparison of pharmacokinetics and anti-pulmonary fibrosis-related effects of sulforaphane and sulforaphane N-acetylcysteine. Pharmaceutics 13: 958 (2021)

2. Y.H. Kim, Y.C. Kim, D.J. Jang, K.A. Min, J. Karmacharya, T.T.L. Nguyen, H.J. Maeng, K.H. Cho. Development of 20(S)-protopanaxadiol-loaded SNEDDS preconcentrate using comprehensive phase diagram for the enhanced dissolution and oral bioavailability. Pharmaceutics 12: 362 (2020)

3. Y.H. Kim, Y.C. Kim, J.Y. Kim, J. Byeon, H.J. Maeng, S.T. Kim, K.A. Min, D.J. Jang, K.H. Cho. Preparation and characterization of tenofovir disoproxil-loaded enteric microparticle. J. Nanosci. Nanotechnol. 20: 5796-5799 (2020)

4. E.J. Heo, S.Y. Park, H.I. Kim, J.H. Sung, H.J. Kwon, J.P. Jee, H.J. Maeng, K.H. Cho, S.T. Kim, Y.C. Kim, S.U. Choi, D.J. Jang. Optimization of hydroxypropyl methylcellulose and dextrin in development of dried nanosuspension for poorly water-soluble drug. J. Nanosci. Nanotechnol. 20: 5813-5818 (2020)

5. Y.C. Kim, K.A. Min, D.J. Jang, T.Y. Ahn, J.H. Min, B.E. Yu, K.H. Cho. Practical approaches on the long-acting injections. J. Pharm. Investig. 50: 147-157 (2020)

6. M.S. Choi, Y.C. Kim, H.J. Maeng. Therapeutic targets of vitamin D receptor ligands and their pharmacokinetic effects by modulation of transporters and metabolic enzymes. J. Pharm. Investig. 50: 1-16 (2020)

7. H.J. Maeng, J-H. Yoon, K-H. Chun, S.T. Kim, D-J. Jang, J-E. Park, Y.H. Kim, S-B. Kim, Y.C. Kim. Metabolic stability of D-allulose in biorelevant media and hepatocytes: comparison with fructose and erythritol. Foods 8: E448 (2019)

8. D.N.K. Trang, Y.C. Kim, S.H. Kwon, C.G. Jang, and H.J. Maeng. Determination of isoorientin levels in rat plasma by ultra-high-performance liquid chromatography coupled with diode array detector and its application to a pharmacokinetic study. Pharmacogn. Mag. 14: 81-86 (2019)

9. H.I. Kim, J.P. Jee, S.T. Kim, D. Kang, Y.C. Kim, H.C. Kim, S.Y. Park, H.M. Lee, K.H. Cho, D.Y. Kim, S.U. Choi, and D.J. Jang. Preparation and characterization of celocoxib nanosuspension using bead milling. J Nanosci Nanotechnol. 19: 1184-1187 (2019)

10. K. Ko, H.J. Kim, P.S. Ho, S.O. Lee, J.E. Lee, C.R. Min, Y.C. Kim, J.H. Yoon, E.J. Park, Y.J. Kwon, J.H. Yun, D.O. Yoon, J.S. Kim, W.S. Park, S.S. Oh, Y.M. Song, W.K. Cho, K. Morikawa, K.J. Lee, and C.H. Park. Discovery of a novel highly selective histamine H4 receptor antagonist for the treatment of atopic dermatitis. J. Med. Chem. 61: 2949-2961 (2018)

11. R.M. Kim, D.J. Jang, Y.C. Kim, J.H. Yoon, K.A. Min, H.J. Maeng, and K.H. Cho. Flurbiprofen-loaded solid SNEDDS peconcentrate for the enhanced solubility, in-vitro dissolution and bioavailability in rats. Pharmaceutics 10: pii: E247 (2018)

12. A. Balla, K.H. Cho, Y.C. Kim and H.J. Maeng. Simultaneous determination of procainamide and N-acetylprocainamide in rat plasma by ultra-high-pressure liquid chromatography coupled with a diode array detector and its application to a pharmacokinetic study in rats. Pharmaceutics 10: pii: E41 (2018)

13. M.H. Kwon, J.N. Yoon, Y.J. Baek, Y.C. Kim, Y.Y. Cho and H.E. Kang. Effects of poloxamer 407-induced hyperlipidemia on hepatic multidrug resistance protein 2 (Mrp2/Abcc2) and the pharmacokinetics of mycophenolic acid in rats. Biopharm Drug Dispos. 37:352-365 (2016)

14. B. Kim, Y.C. Kim and B. Park. Pomolic acid inhibits metastasis of HER2 overexpressing breast cancer cells through inactivation of the ERK pathway. Int J Oncol. 49:744-752 (2016)

15. J.H. Kim, Y.C. Kim and B. Park. Hispolon from Phellinus linteus induces apoptosis and sensitizes human cancer cells to the tumor necrosis factor-related apoptosis-inducing ligand through upregulation of death receptors. Oncol Rep. 35:1020-1026 (2016)

16. S.Y. Han, B.H. You, Y.C. Kim, Y.W. Chin and Y.H. Choi. Dose-independent ADME properties and tentative identification of metabolites of α-mangostin from garcinia mangostana in mice by automated microsampling and UPLC-MS/MS methods. PLoS One. 10:e0131587 (2015)

17. Y.C. Kim, I.B. Kim, C.K. Noh, H.P. Quach, I.S.Yoon, E.C. Chow, M Kim, H.W. Jin, K.H. Cho, S.J. Chung, K.S. Pang and H.J. Maeng. Effects of 1α,25-dihydroxyvitamin D3 , the natural vitamin D receptor ligand, on the pharmacokinetics of cefdinir and cefadroxil, organic anion transporter substrates, in rat. J Pharm Sci. 103:3793-3805 (2014)

18. M.R. Choi, M.H. Kwon, Y.Y. Cho, H.D. Choi, Y.C. Kim and H.E. Kang. Pharmacokinetics of tolbutamide and its metabolite 4-hydroxy tolbutamide in poloxamer 407-induced hyperlipidemic rats. Biopharm Drug Dispos. 35:264-274 (2014)

19. H.E. Jin, I.B. Kim, Y.C. Kim, K.H. Cho and H.J. Maeng. Determination of cefadroxil in rat plasma and urine using LC-MS/MS and its application to pharmacokinetic and urinary excretion studies. J Chromatogr B Analyt Technol Biomed Life Sci. 947-948:103-110 (2014)

- 한양대학교 약학대학 약학과

- 한국가스공사 자원개발연구센터 인턴 연구원

- 한국마사회 도핑검사소 과장

- Visiting Researcher, Australia Forensic Racing Laboratory (AFRL), Sydney, Australia

- Adjunct Instructor (Pharmaceutical analysis), Department of Pharmacy, Jeju University

- Assistant Professor, Department of Pharmaceutical Engineering, Inje University

- 대한약학회 종신회원 (The Pharmaceutical Society of Korea)

- 한국분석과학회 회원 (The Korean Society of Analytical Sciences member)

- 한국질량분석학회 종신회원 (Korean Society for Mass Spectrometry member)

- Member of Association of Official Racing Chemist (AORC), USA

- Associate editor, Drug Targets and Therapeutics (DTT)

- Pharmaceutical & Clinical Analysis

- Forensic Analysis (Doping Control)

- Natural Product Analysis

- Metabolomics

- Molecular Networking based Mass Spectrometry

- Absorption, Distribution, Metabolism, Excretion (ADME)

- Pharmacokinetics

- Drug-Drug Interaction

- 의약품분석학

- 기기분석학

- 첨단바이오분석학

- 기기분석실험

- 약품분석품질관리

- 첨단오믹스학

Under review

1. A Versatile Toolkit for Drug Metabolism Studies with GNPS2: from Drug Development to Clinical Monitoring, Nature Protocols, 2025 (Coauthor)

Published

Young Beom Kwak*, Jundong Yu*, Jungho Yoon* “Pharmacokinetic interaction of red ginseng with furosemide in horses”, ICRAV HONG KONG 2023, 2024.

Young Beom Kwak, Soo Ah Seo, Myunghoo Kim*, Jungho Yoon** "Identification of altered blood metabolic pathways in equines following ethyl pyruvate administration using non-targeted metabolomics", Scientific Reports, 2024, 14, 27684.

Young Beom Kwak, Ilia Stambler, Hye Hyun Yoo*, Jungho Yoon*, “Metabolomic analysis of the impact of red ginseng on equine physiology, Front Vet Sci, 2024

Jeong In Seo, Young Beom Kwak, Seong Eun Cho, Hye Hyun Yoo*, “An in silico-guided Approach for Assessing Herb-Drug Interaction Potential: A Case Study with Cudrania tricuspidata leaf Extracts”, Planta Medica, 2024.

Young Beom Kwak†, Jungho Yoon†, Jundong Yu*, Hye Hyun Yoo*, “Intravenous Pharmacokinetic Study of Detomidine and Its Metabolites in Equines for Misuse Prevention in Doping Control”, Drug Targets and Therapeutics, 2024.

Young Beom Kwak, Jungho Yoon, Hye Hyun Yoo*, “Rapid investigating of phase I metabolites of SR9009 in vitro horse liver microsomes via feature-based molecular networking approach: Potential applications in doping control”, J Pharm Biomed Anal, 2024 246, 116190

Jungho Yoon, Ahram Kim, Jongyoung Park, Young Beom Kwak, In-Soo Choi, Taemook Park* “Secondary Small Intestinal Obstruction Associated with an Omental Adhesion after End-to-end Jejuno-ileal Anastomosis in a Thoroughbred Horse”, Slovenian Veterinary Research, 2024

Young Beom Kwak, Hye Hyun Yoo and Jungho Yoon* “The Impact of the Administration of Red Ginseng (Panax ginseng) on Lipid Metabolism and Free Fatty Acid Profiles in Healthy Horses Using a Molecular Networking Approach”, Front Vet Sci, Frontiers, 2024

Dong-Ha Lee, Kyungmin Jang, Taemook Park, Youngjong Kim, Kyoung Hwan Kim, Eun-bee Lee, Young Beom Kwak, Eun-Ju Ko “Evaluation of concurrent immunizations with equine influenza virus and strangles vaccines”, Korean Journal of Veterinary Service, 2023

Young Beom Kwak†, Jeong In Seo†, Hye Hyun Yoo*, “Exploring Metabolic Pathways of Anamorelin, a Selective Agonist of the Growth Hormone Secretagogue Receptor, via Molecular Networking”, Pharmaceutics, 2023, 15(12), 2700

Young Beom Kwak, Eunkyu Lee, Hyunjoo Choi, Taemook Park, Ahram Kim, Jungon Kim, Jungho Yoon*, Hye Hyun Yoo*, “A Pharmacokinetic Study on Red Ginseng with Furosemide in Equine”, Front Vet Sci, 2023, 10.

Young Beom Kwak*, Min Sun Choi “Identification of a metabolite for the detection of the hydrophilic drug diisopropylamine for doping control”, J Pharm Biomed Anal, 2023 234(20);115576.

Young Beom Kwak, Shaheed Ur Rehman, Hye Hyun Yoo* “Quantification of three prohibited anabolic-androgenic steroids in equine urine using gas chromatography-tandem mass spectrometry”, Mass Spec Letters, 2023 13(4).

Young Beom Kwak, Jundong Yu* and Hye Hyun Yoo* “Simultaneous liquid chromatography tandem mass spectrometric determination of 35 prohibited substances in equine plasma for doping control”, Mass Spec Letters, 2023 13(4).

Young Beom Kwak, Jundong Yu* and Hye Hyun Yoo* “A quantitative method for the simultaneous detection of SR9009 and SR9011 in equine plasma using liquid chromatography-electrospray ionization-tandem mass spectrometry”, Drug Test Anal, 2022 14(8):1532-1538.

Young Beom Kwak, Eo Jin Im, Bok Son Jeong, Jundong Yu* and Hye Hyun Yoo* “Study of cobalt doping control via various routes in thoroughbred horses”, Drug Test Anal, 2022 14(4):718-723.

· 중앙대 약대 학사 (약사면허: 42281)

· 서울대 대학원 물리약학 석사 (1996.2)

· 서울대 대학원 물리약학 박사 (2001.2)

· 삼양사 중앙연구소 책임연구원/수석연구원 (프로젝트 리더)

· 삼양바이오팜 의약바이오연구소 수석연구원 (팀장)

· 유영제약 중앙연구소 상무 (연구소장)

· 인제대학교 제약공학과 (2023.9~현재)

<학회활동>

 2003-2006, 2008, 2010, 2011, 2013, 2015: 한민족과학기술자네트워크 (KOSEN) 전문가 

 2018.01~현재: 한국약제학회 학술위원회 위원

 2022.11~현재: 미국약제학회 (AAPS) 정회원

 2021: 제어방출학회 (CRS) 정회원

<정부과제 참여 경험> 

1. 보건복지부 보건의료기술 진흥사업 (2004 5~2006.3, 16.7억원, 참여연구원 실무책임자) 

2. 보건복지부 혁신형 연구중심병원사업 (2006 12~2011 11, 25.6억원, 참여연구원 실무책임자) 

3. 보건복지부 보건의료연구개발사업 (2009 12~2011 11, 8.93억원, 연구책임자) 

4. 보건복지부 혁신형제약기업 국제공동연구지원사업 (2014 10~2016 9, 16.68억원, 연구책임자) 

5. 사업자원부 산업핵심기술개발사업 (2017 3~ 2019.12, 56.3억원, 참여연구원)

<기업부설 연구소 경력>

· 삼양: 프로젝트 리더 및 연구책임자로서 총 30건의 연구과제 수행, 9건의 제품화 실적

· 유영: 총22건의 제품화 과제 관리, 품목허가 5건, 생물학적동등성 시험 통과 6건, 공장기술이관 8건, 의동/생동/임상/PV생산 8건, 신규과제 도출 6건, C&D수행 총 21건

· 신약 Preformulation및 신제형 개량신약 제제설계 

· 난용성약물의 가용화 및 체내흡수 증진 연구 

· 초미세입자성 약물전달체 연구 

· 작용부위 표적나노전달체 연구

· 생분해성/생체적합성 고분자 약물 전달체 개발 

· 온도감응성약물 전달체연구- 하이드로젤 연구 

· 지속방출 제형 연구- 서방형마이크로입자, 서방형액상Depot연구

· DDS 개량신약 대량생산공정연구 (CMC)

· 물리약학

· 약제학

· 의약품 품질관리

· 약제학 실험

· 캡스톤디자인

<논문목록>

1. So-Youn Ro, Hyeon-Muk Choi, Seung-Ho Choi, Sa-Won Lee, Soo-Jeong Lim, Tricaprin as a membrane permeability regulator: sustained small hydrophilic substance release from liposomes Journal of Pharmaceutical Investigation (2023) 53:539.548

2. Sang Yeob Park, Zion Kang Prakash Thapa, Yong Suk Jin, Joo Won Park, Hye Jung Lim, Jae Young Lee, Sa-Won Lee, Min-Hyo Seo, Min-Soo Kim, Seong Hoon Jeong, Development of sorafenib loaded nanoparticles to improve oral bioavailability using a quality by design approach. Int J Pharm. 20;566:229-238, 2019. 

3. Seung Hwan Lee, Jun Gi Hwang, Sang Yeob Park, Hye Jung Lim, Sa-Won Lee, Min-Hyo Seo, Jae Woo Kim, Jang Hee Hong, Single-Dose Comparative Pharmacokinetics of Two Formulations of Lenalidomide 25 mg in Healthy Subjects: A Randomized Crossover Study. Adv Ther. 35(2):210-217, 2018

4. Jin Park, Seok Soon Park, Kyoung Jin Lee, Eun Jin Ju, Seol Hwa Shin, Eun Jeong Ko, Sa-Won Lee, Min Hyo Seo, Jung Shin Lee, Si Yeol Song, Seong-Yun Jeong, Eun Kyung Choi, Docetaxel-polymeric nanoparticle enhances radiotherapeutic efficacy in human pancreatic cancer, Transl Cancer Res 7(1):60-67, 2018

5. Si Yeol Song, Kyu-pyo Kim, Seong-Yun Jeong, Jin Park, Jaesook Park, Joohee Jung, Hye Kyung Chung, Sa-Won Lee, Min Hyo Seo, Jung-shin Lee, Kyung Hae Jung, Eun Kyung Choi, Polymeric nanoparticle-docetaxel for the teatment of advanced solid tumors: phase I clinical trial and preclinical data from an orthotopic pancreatic cancer model, Oncotarget, 7(47):77348-77357, 2016.

6. Joohee Jung, Sung-Jin Park, Hye Jyung Chung, Hye-Won Kang, Sa-Won Lee, Min-Hyo Seo, Heon Joo Park, Si Yeol Song, Seong-Yun Jeong, H Eun Kyung Choi, Polymeric nanoparticles containing taxanes enhance chemoradiotherapeutic efficacy in non-small cell lung cancer, Int. J. Radiation Oncology, 84(1):77-83. 2012.

7. Ha Na Woo, Hye Jyung Chung, Eun Jin Ju, Joohee Jung, Hye-Won Kang, Sa-Won Lee, Min-Hyo Seo, Jin Seong Lee, Jung Shin Lee, Heon Joo Park, Si Yeol Song, Seong-Yun Jeong, Eun Kyung Choi, Polymeric nanoparticles containing taxanes enhance chemoradiotherapeutic efficacy in non-small cell lung cancer, Int. J. Radiation Oncology, 84(1):77-83. 2012.

8. Ha Na Woo, Hye Jyung Chung, Eun Jin Ju, Joohee Jung, Hye-Won Kang, Sa-Won Lee, Min-Hyo Seo, Jin Seong Lee, Jung Shin Lee, Heon Joo Park, Si Yeol Song, Seong-Yun Jeong, Eun Kyung Choi, Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy, Int. J. Nanomedicine, 7, 1-12, 2012

9. Sa-Won Lee, Min-Hyuk Yun, Seung Wei Jeong, Chang-Hoon In, Ji-Young Kim, Min-Hyo Seo, Chaul-Min Pai, Sun-Ok Kim, Development of docetaxel-loaded intravenous formulation, Nanoxel-PM™ using polymer-based delivery system, J. Cont. Rel. 155, 262-271, 2011

10. Sa-Won Lee, Dong-Hoon Chang, Myung-Seop Shim, Bong-Oh Kim, Sun-Ok Kim, and Min-Hyo Seo, Ionically Fixed Polymeric Nanoparticles as a Novel Drug Carrier, Pharm. Res., 24(8), 1508-1516, 2007 

11. Bryan Howard, Zhoinggao Gao, Sa-Won Lee, Min-Hyo Seo, and Natalya Rapoport, Ultrasound-Enhanced Chemotherapy of Drug-Resistant Breast Cancer Tumors by Micellar-Encapsulated Paclitaxel. Am. J. Drug Deliv. 4(2); 97-104, 2006

12. Eun-Jin Lee, Sa-Won Lee, Han-Gon Choi and Chong-Kook Kim, Bioavailability of Cyclosporin A dispersed in Sodium Lauryl Sulfate-Dextrin based Solid Nanospheres, Int. J. Pharm., 218, 125-131, 2001

13. Sa-Won Lee, Moon-Hee Kim and Chong-Kook Kim, Encapsultion of ethanol by spray drying technique: Effect of sodium lauryl sulfate, Int. J. Pharm., 187, 193-198 (1999)

14. Sa-Won Lee, Han-Gon Choi, Mi-Kyung Lee, Zhong-Gao Gao, In-Sook Kim and Chong-Kook Kim, Trials of in situ-gelling and mucoadhesive acetaminophen liquid suppository in human subjects, Int. J. Pharm., 174, 201-207 (1998)

<학술회의 발표>

1. 이사원, Polymer-based nanomedicines for treatment of cancer, 한국약제학회 국제학술대회, The K Hotel서울 가야금홀, 2019.11.22 구두발표, 

2. 이사원, Polymeric micelle-based nanomedicines for treatment of cancer, Asia Pacific Consortium of Gene and Cell Therapy (APCGCT) 연례총회 및 학술대회, Hanyang Institute of Technology (HIT) center, 2019.11.8 구두발표

3. 이사원, Research trends in polymeric nanocarriers for drug delivery systems, 대한약학회 추계국제학술대회 물리약학분과 심포지움, Yeosu Expo Convention Center, 2019.10.15 구두발표

4. H. J. Lim, I. J. Choi, J. Y. Lee, M. H. Yun, S. W. Cho, S. W. Jeong, J. Y. Kim, S. W. Lee Development of Oral Solid Dosage Form for Sunitinib Free Base with Improved pH-Dependent Dissolution Rate and Absorption, AAPS PharmSci360, November 3–6, 2019, Henry B. Gonzalez Convention Center, San Antonio, Texas, USA

5. Jiyeong Kim, Inja Choi, Sa-Won Lee and Sukyen Ko, Development and validation of a quantitative method for fulvestrant in rat plasma by LC-MS/MS, AAPS PharmSci360, November 3–6, 2019, Henry B. Gonzalez Convention Center, San Antonio, Texas, USA

6. S. Y. Park, Z. Kang, J. W. Park, Y.S. Jin, H. J. Lim, J. Y. Lee, M. H. Yun, S. W. Cho, S. W. Jeong, J. Y. Kim, Y. J. Yoon, S. W. Lee, Fasted and Fed Bioequivalence Study of Sorafenib Tablet (SYO-1644) in Beagle Dogs, AAPS PharmSci360, November 3–6, 2019, Henry B. Gonzalez Convention Center, San Antonio, Texas, USA

7. Goo-Young Kim, Gyeong Hae Kim, Seung-Wei Jeojng, Minhyuk Yun, Sa-Won Lee, Chang-Hoon In, Geun Woo Jin, Gyu-Young Moon, Sang Woo Jo, Hyun-Jung Lee, Chemotherapy with Nanoparticles Platform Enhances Immunogenic Cell Death in Syngeneic Mice Model of Colon Cancer, AAPS PharmSci360, Nov,4-7, 2018, Washington DC, USA

8. J.Y. Lee, S.Y. Park, H.J.Lim, S.W. Lee, M.H. Yun, S.W Jeong, J.Y. Kim, Y.J.Yoon, M.H, Seo, Solid Dispersion of Sorafenib Tosylate with Enhanced Solubility and Bioavailability, AAPS PharmSci360, Nov,4-7, 2018, Washington DC, USA

9. H.J.Lim, S.Y. Park, J.Y. Lee, S.W. Lee, M.H. Yun, S.W.Cho, S.W Jeong, J.Y. Kim, Y.J.Yoon, Z. Kang, J.W. Park, Y.S. Jin, M.H, Seo, Pharmacokinetics study of sorafenib tablet (SYO1644) with improved bioavailability in Beagle dogs, AAPS PharmSci360, Nov,4-7, 2018, Washington DC, USA

10. S.Y. Park, Z. Kang, Y.S. Jin, J.W. Park, H.J. Lim, J.Y. Lee, S.W. Lee, M.H. Seo, M.S. Kim, S.H.Jeong, Optimization of Nanoparticle Processing to Improve Bioavailability Based on Quality by Design Approach, Controlled Release Society (CRS) Annual Meeting, July 22-24, 2018, New York, USA

11. Sa-Won Lee, Joong-Woong Cho, Gyeong-Hae Kim, Min-Hyuk Yun, Seung-Wei Jeong, Min-Hyo Seo, Reformulation of Temsirolimus using polymeric micelle technology to improve tolerability, Controlled Release Society (CRS) Annual Meeting, July 22-24, 2018, New York, USA

12. S.Y. Park, H.J. Lim, J.Y. Lee, S.W.Lee, M.H. Yun, S.W. Cho, S.W. Jeong, J.Y. Kim, Y.K. Yoon, Z. Kang, J.W. Park, Y.S. Jin, M.H. Seo, Dissolution rate and bioavailability enhancement of nanoparticulate sorafenib composition, 2017 AAPS Annual Meeting & Exposition, Nov. 12~15, 2017 (San Diego, USA)

13. Lee S. Hwang JG, Park SY, Lim HJ, Lee SW, Seo MH, Kim J, Hong JH, Single-Dose comparative pharmacokinetics of two formulations of lenalidomide 25 mg in healthy volunteers, 2017 AAPS Annual Meeting & Exposition, Nov. 12~15, 2017 (San Diego, USA)

14. 이사원, Polymer-based nanomedicines for treatment of cancer, 식약처 주관 나노안정성 전문가 워크숍, 2017.9.15 구두발표

15. 이사원, Development of nanomedicines for treatment of cancer using amphiphilic and biodegradable polymeric nanocarriers, 2017 화학공학회 제14회 약물전달 및 화장품 기술심포지움, 2017.10.27구두발표

16. Sa-Won Lee, Gyeong-Hae Kim, Hye-Jin Jang, Yilwoon Yi, Minhyo Seo, Development of a novel in vitro release test method for a polymeric micelle formulation for paclitaxel, Genexol-PM, Controlled Release Society (CRS) Annual Meeting, July 17-20, 2016, Seattle, Washington, USA

17. S.Y.Park, H.J. Lim, S.W. Lee, M.H. Yun, J.Y.Kim, K.J. Kyung, S.W. Jeong, M.H. Seo, Development of bioequivalent lenalidomide tablet to Revlimid® Capsule, 2016 AAPS Annual Meeting & Exposition, Nov. 11~17, 2016 (Colorado, Denver, USA)

18. 이사원, Advances on drug delivery systems for lung cancer, 2016년 대한폐암학회 표적치료연구회 춘계학술대회, 2016. 3. 26 구두발표

19. 이사원, 암치료를 위한 고분자 기반 나노의약품의 개발, 식품의약품안전평가원 의약품연구회 전문가 초청 세미나, 2016.3.28 구두발표

20. 이사원, Polymeric Nanoparticles as anticancer drug carrier, 나노기술 응용연구회 세미나 (세종대학교), 2016.2 구두발표

21. Sa-Won Lee, Hey-Won Kang, Do-Hoon Kim, Ji-Young Kim, Min-Hyuk Yoon, Chang-Hoon In, Seung-Wei Jeong, Sun-Ok Kim, Bum-Chan Min, Min-Hyo Seo, THE INFLUENCE OF BIWEEKLY REPEATED DOSE AND PREMEDICATION ON PHARMACOKINETICS OF PACLITAXEL-LOADED POLIMERIC NANOPARTICLES IN BEAGLE DOGS, 2010 AAPS Annual Meeting & Exposition, Nov. 14-18, 2010 (New Orleans, USA) 

22. Joohee Jung, Jin-Beom Bea, Ran Ji Yoo, Seong-Yun Jeong, Hye-Won Kang, Sa-Won Lee, Min-Hyo Seo, Hye Kyung Chung, Eun Kyung Choi, Improvement of anticancer effect by the combination of polymeric nanoparticle-docetaxel and irradiation 대한암학회 June 10-11, 2010, Lotte Hotel, Seoul, Korea 

23. Joohee Jung, Jin-Beom Bea, Ran Ji Yoo, Seong-Yun Jeong, Hye Kyung Chung, Hye-Won Kang, Sa-Won Lee, Min-Hyo Seo, Eun Kyung Choi, Improvement of radiotherapeutic efficacy by polymeric nanoparticle-docetaxel, Japan DDS Society, Annual Meeting, June 17-18, 2010, Osaka, Japan 

24. Ha-Na Woo, Eun Jin Ju, Seong-Yun Jeong, Sung-Jin Park, Joohee Jung, Sa-Won Lee, Hye-Won Kang, Bong-Oh Kim, Min-Hyo Seo, Eun Kyung Choi, Radiosensitization effect of polymeric nanoparticle-sirolimus on human cancer cells, Particles 2010, May 22-25, 2010, Orlando, USA 

25. Sa-Won Lee, Hey-Won Kang, Bong- Oh Kim, Min-Hyuk Yun, Seung-Wei Jeong, Sun-Ok Kim, Seong-Yun Jeong, Eun-Kyung Choi, Min-Hyo Seo, and Chaul-Min Pai, Docetaxel-loaded ionically fixed polymeric nanoparticles (SYP-0709) as a novel docetaxel formulation with improved anti-tumor efficacy, 10th US-Japan Symposium on Drug Delivery Systems, December 16-20, 2009, The Westin Maui Lahaina, Maui, Hawaii 

26. Sa-Won Lee, Hey-Won Kang, Bong- Oh Kim, Seung-Wei Jeong, Sun-Ok Kim, Sung-Jin Park, Joohee Jung, Ha-Na Woo, Seong-Yun Jeong, Eun-Kyung Choi, Min-Hyo Seo, PACLITAXEL-LOADED IONICALLY FIXED POLIMERIC NANOPARTICLES AS A NOVEL RADIOSENSITIZER, 2009 AAPS Annual Meeting & Exposition, Nov. 8-12, 2009 (Los Angeles, USA) 

27. Ha-Na Woo, Seong-Yun Jeong, Sung-Jin Park, Joohee Jung, Hye-Won Kang, Sa-Won Lee, Bong-Oh Kim, Min-Hyo Seo, Eun Kyung Choi, Radiosensitization effect of polymeric mTOR inhibitor complex on human cancer cells, 2nd Asian Congress of radiation research, May 17-20, 2009, COEX, Seoul, Korea 

28. Sung-Jin Park, Joohee Jung, Seong-Yun Jeong, Ha-Na Woo, Hye-Won Kang, Sa-Won Lee, Bong-Oh Kim, Min-Hyo Seo, Eun Kyung Choi, Radiosensitising effect of polymeric nanoparticle-paclitaxel, Controlled Release Society (CRS), Annual Meeting, July 18-22, 2009, Copenhagen, Denmark 

29. 이사원, Ionically fixed polymeric nanoparticles as novel drug carrier, 서울대종합약학연구소 심포지움 (서울대학교), 2007.12 구두발표 

30. 김선옥, 이연희, 정승의, 강송이, 최지연, 서민효, 이사원, 오헌승, Genexol-PM®, a polymeric micellar paclitaxel formulation, suppresses primary tumor growth and lung metastasis in a green fluorescent protein orthotopic model of breast and pancreatic cancer. 97th Annual Meeting & Exposition of American Association for Cancer Research (AACR), 2006. 6 (Washington DC, USA) 

31. Sa-Won Lee, Myung-Han Hyun , Jeong-Il Yu , Dong-Hoon Chang , Sun-Ok Kim, Bong-Oh Kim , Min-Hyo Seo, Hun-Seung Oh, Biodistribution and Excretion Study of [3H]Paclitaxel-Containing Polymeric Nanoparticles (3H-Azurexol™) in Tumor-Bearing Nude Mice. 33rd Annual Meeting & Exposition of the Controlled Release Society (CRS), 2006 (Vienna, Austria) 

32. 김선옥, 이연희, 정승의, 강송이, 최지연, 서민효, 이사원, 오헌승, Genexol-PM®, a polymeric micellar paclitaxel formulation, suppresses primary tumor growth and lung metastasis in a green fluorescent protein orthotopic model of breast cancer. 대한약학회 

33. Sa-Won Lee, Myung-Han Hyun , Jeong-Il Yu , Dong-Hoon Chang , Sun-Ok Kim, Bong-Oh Kim , Min-Hyo Seo, Hun-Seung Oh, Novel Polymeric Nanoparticles for Improving Therapeutic Effect of Anti-Mitotic Agents. 32nd Annual Meeting & Exposition of the Controlled Release Society (CRS), 2005 (Florida, USA) 

34. Sa-Won Lee, Myung-Han Hyun , Jeong-Il Yu , Dong-Hoon Chang , Sun-Ok Kim, Bong-Oh Kim , Min-Hyo Seo, Hun-Seung Oh, Paclitaxel-containing Polymeric Nanoparticles (Azurexol™) For Overcoming Paclitaxel-Resistant Cancer. AAPS Annual Meeting & Exposition, 2004, 11 (Baltimore, USA), AAPSPharmSci Vol. 6, No. 4, Abstract W5212 (2004)

35. Sa-Won Lee, Myung-Han Hyun , Jeong-Il Yu , Dong-Hoon Chang , Bong-Oh Kim , Hey-Jeong Yoon, Jeong-Kyung Kim, Min-Hyo Seo, Hun-Seung Oh, Ionically Fixed Polymeric Nanoparticles As A Novel Drug Carrier For Poorly Water-soluble Drugs. AAPS Annual Meeting & Exposition, 2003, 11 (Utah, USA), AAPSPharmSci Vol. 5, No. 4, Abstract W4139 (2003) 

36. Sa-Won Lee, Myung-Han Hyun , Jeong-Il Yu , Dong-Hoon Chang , Bong-Oh Kim , Min-Hyo Seo, Hun-Seung Oh, Ionically Fixed Polymeric Micelles As A Novel Drug Carrier. AAPS Annual Meeting & Exposition, 2002, 11 (Toronto, Canada), AAPSPharmSci Vol. 4, No. 4, Abstract W4202 (2002) 

37. S. Lee, M. Hyun, J. Yu, D. Jang, B. Kim, M. Seo, H. Oh, EFFECT OF D,L-POLYLACTIC ACID (D,L-PLA) ON PHYSICOCHEMICAL CHARACTERISTICS AND PHARMACOKINETICS OF PACLITAXEL-CONTAINING POLY(ETHYLENE OXIDE)-POLY(LACTIC ACID) (mPEG-PLA) POLYMERIC MICELLES, Proceedings of the 29th Annual Meeting of the Controlled Release Society, 2002. 7 (Seoul, Korea). 

38. S.-W. Lee and C.-K. Kim THERMO-REVERSIBLE MICROEMULSIONS AS TOPICAL DRUG DELIVERY SYSTEMS FOR A POORLY-WATER SOLUBLE DRUG, PROSTAGLANDIN E1, Proceedings of the 28th Annual Meeting of the Controlled Release Society, 2001. 7(San Diego, USA). 

39. Han-Gon Choi, Sa-Won Lee, Mi-Kyung Lee and Chong-Kook Kim, Trials of in situ-gelling and mucoadhesive acetaminophen liquid suppository in human subjects. AAPS Annual Meeting & Exposition, 1998, 11. 15-19. (San Francisco, California) 

40. S. Lee, K. Kim, C. Kim, Effects of sodium lauryl sulfate on the encapsulation of ethanol by spray-drying technique, Proceed Intern. Symp. Control. Rel. Bioact. Mater., 23, 359-360(1996) - Controlled Release Society, Inc., 1996. 7(Kyoto, Japan). 

41. 이사원, 최한곤, 박정일, 김종국, 홍삼엑기스를 함유한 분말주의 제조 및 평가, 고려인삼학회 춘계학술대회 및 총회, pp25-26, 한국인삼연초연구원 (대전). 

42. Sa-Won Lee, Moon-Hee Kim, Chong-Kook Kim and , Encapsulation of ethanol by spray drying technique: Effect of sodium lauryl sulfate, 대한약학회 춘계총회 및 학술대회, pp.263, 1999. 4. 22-23. 전남대학교 (광주). 

43. 이사원, 김종국, 분무건조법을 이용한 이부프로펜 분말엘릭실제의 제조에 미치는 황산라루릴 나트륨(SLS)의 영향, 제45회 대한약학회 추계학술대회, 1996. 10.25-26. (숙명여자대학교) 

44. Sa-Won Lee and Chong-Kook Kim, Effects of sodium lauryl sulfate on the encapsulation of ethanol by spray-drying technique,한국응용약물학회, 1996.4.18-19 (서울대학교 문화관) 

45. 이사원, 김종국, 분무건조법을 이용한 덱스트린 피막내 에탄올 봉입에 미치는 황산 라우릴 나트륨(SLS)의 영향 평가, 대한약학회, 1995.10.27-28 (성균관대 약대) 

<특허목록 (등록 특허)> 

국내외 총 66건 출원 특허 중 최근 3년내 등록된 특허 31건

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서울대학교 약학대학 제약학과

· Ph.D., Pharmaceutics, College of Pharmacy, Seoul National University

· Leader, AmorePacific Corporation R&D Unit, Amorepacific Corp. 

· Post-doctorate, Department of Chemistry, University of Massachusetts

· Research Professor, College of Medicine, Korea University

· 한국약제학회 간사 (Financial manager, The Korean Society of Pharmaceutical Science and Technology)

· 대한화장품학회 회원 (Member, The Society of Cosmetic Scientists of Korea)

· Therapeutic Biologics and Bioactives (Gene therapeutics, cell therapeutics, and peptide/protein therapeutics)

· Drug Delivery System, Drug Development

· Cosmetics/Skin biology

· Interdisciplinary, Translational Research 

· Biology (Undergraduate course)

· Process Validation (Undergraduate course)

· Biochemistry (Undergraduate course)

· Physiology (Undergraduate course)

· Biopharmaceutics, Drug Delivery System (Graduate course)

SCI/SCIE peer-reviewed 2010-2024

1. Kim E, Kim H, Jang D, Kim S, Kim ST. Micronized dry emulsion with solid nanocore: a novel strategy to incorporate a large amount of ceramides. J Ind Eng Chem. 2024. 135, 596-602.

2. Kim SY, Guk D, Jeong Y, Kim E, Kim H, Kim ST. Engineered hybrid vesicles and cellular internalization in mammary cancer cells. Pharmaceutics. 2024, 16(4), 440.

3. Park PJ, Mondal H, Pi BS, Kim ST, Jee JP. The effect of oxygen supply using perfluorocarbon-based nanoemulsions on human hair growth. J Mater Chem B. 2024. 12(4), 991-1000.

4. Kim Y, Kim S, Choi S, Nguyen T, Ahn S, Jung H, Jee JP, Choi H, Jang D. Development and evaluation of self-microemulsifying drug delivery system for improving oral absorption of poorly water-soluble olaparib. Pharmaceutics. 2023. 15(6), 1669.

5. Kim H, Kim ST, Park DB, Cho H, Asadujjaman M, Jee JP. Tripheylphosphonium modified mesoporous silica nanoparticle for enhanced algicidal efficacy of cyclohexyl-(3.4-dichlorobenzyl) amine. Int J Mol Sci. 2022. 23(19), 11901.

6. Choi SA, Park EJ, Lee JH, Min KA, Kim ST, Jang DJ, Maeng H, Jin SG, Cho KH. Preparation and characterization of pazopanib hydrochloride-loaded four component self nanoemulsifying drug delivery systems preconcentrate for enhanced solubility and dissolution. Pharmaceutics. 2022, 14(9), 1875.

7. Lee SY, Kim SY, Ku SH, Park EJ, Jang DJ, Kim ST, Kim S. Polyhydroxyalkanoate decelerates the release of paclitaxel from poly(lactic-co-glycolic acid) nanoparticles. Pharmaceutics. 2022, 14(8), 1618.

8.  Lim H, jin S, Jeong Y, Kim S, Jang D, Kim ST. Preparation of hydroxypropyl-β-cyclodextrin-incorporated liposomes and evaluation of their rapid release property. J Ind Eng Chem. 2021, 100(25), 59-62. 

9. Choi SA, Park EJ, Kim YH, Jee JP, Kim ST, Jang DJ, Min KA, Cho KH. Screening of electrolyte complexes formed between dextran sulfate and amine structures of small-molecule drugs. J Nanosci Nanotechnol. 2021, 21(7), 3679-3782.  

10.  Hwang Y, Cho KH, Kim H, Kim H, Kim ST, Lee JG, Cheon SH, Choi S, Park HJ, Jang J, Choi S, Lee K, Park SY, Jang D. Surface activity and emulsifying effect of nontoxic starch nanocrystal. J Nanosci Nanotechnol. 2021, 21(7), 4051-4054

11.  Cheon S, Park S, Sung J, Lee JG, Choi S, Jang J, Kim H, Kim ST, Jeong S, Lee K, Jang D. Preparation and evaluation of nanostructured lipid nanocarrier for topical delivery of velutin: synthetic tyrosinase inhibitor. J Nanosci Nanotechnol. 2021, 21(7), 4093-4097

12.  Lim H, Kwon D, Park PJ, Bin B, Kim S, Park SY, Cho KH, Jang D, Kim ST. Topical delivery of nanosized hydroxycitric acid enriched extract-loaded ethosomes for suppreesion of lipid droplet deposition. J Nanosci Nanotechnol. 2021, 21(7), 4089-4092

13. Jo H, Cha B, Kim H, Brito S, Kwak BM, Kim ST, Bin B, Lee M. α-Pinene enhances the anticancer activity of natural killer cells via ERK/AKT pathway. Int J Mol Sci., 2021, 22(2), 656. 

14. Choi KH, Kim ST, Bin B, Park PJ. Effect of konjac glucomannan (KGM) on the reconstitution of the dermal enviroment against UVB-induced condition. Nutrients 2020, 12(9), 2779. 

15. Heo E, Park SY, Kim H, Sung J, Kwon HJ, Jee J, Maeng M, Cho KH, Kim ST, Kim YC, Choi S, Jang D. Optimization of hydroxypropyl methyl cellulose and dextrin in development of dried nanosuspension for poorly water-soluble drug. J Nanosci Nanotechnol. 2020, 20(9), 5813-5818. 

16. Park PJ, Kim ST. Caveolae-associated protein 3 (Cavin-3) influences adipogenesis via TACE-mediated Pref-1 shedding. Int J Mol Sci. 2020, 21(14), 5000. 

17. Kim YH, Kim Y, Kim JY, Byeon J, Maeng H, Kim ST, Min KA, Jang D, Cho KH. Preparation and characterization of tenofovir disoproxil-loaded enteric microparticle. J Nanosci Nanotechnol. 2020, 20(9), 5796-5799. 

18. Ryu K, Park PJ, Kim S, Bin B, Jang D, Kim ST. Topical delivery of coenzyme Q10-loaded microemulsion for skin regeneration, Pharmaceutics 2020, 12(4), 332. 

19. Kim W, Lee EJ, Bae I, Myoung K, Kim ST, Park PJ, Lee K, Pham AV, Ko J, Oh SH, Cho E. Lactobacillus plantarum-derived extracellular vesicles induce anti-inflammatory M2 macrophage polarization in vitro. J Extracell Vescles 2020, 9(1), 1793514. 

20. Heo E, Park SY, Kim H, Sung J, Kwon HJ, Jee J, Maeng H, Cho KH, Kim ST, Kim YC, Choi S, Jang D. Optimization of HPMC and dextrin in development of dried nanosuspension for poorly water-soluble drug. J Nanosci Nanotechnol. 2019, 20(9), 5813-5818

21. Maeng HJ, Yoon JH, Chun KH, Kim ST, Jang DJ, Park JE, Kim YH, Kim SB, Kim YC. Metabolic Stability of D-Allulose in Biorelevant Media and Hepatocytes: Comparison with Fructose and Erythritol. Foods. 2019, 8(10), 48. 

22. Choi SU, Kim ST, Han DG, Hwang YH, Lee KY, Kim DU, Cho KH, Park SY, Kim HC, Kim SB, Jang DJ. Comparative Assessment of Biological Activities of Mistletoes for Cosmetic Applications: Viscum Album Var. Coloratum (Kom.) Ohwi and Loranthus Tanakae Franch. & Sav. J Cosmet Sci. 2019, 70(5), 235-245. 

23. Lee MG, Choi MA, Chae S, Kang MA, Jo H, Baek JM, In KR, Park H, Heo H, Jang D, Brito S, Kim ST, Kim DO, Lee JS, Kim JR, Bin BH. Loss of the dermis zinc transporter ZIP13 promotes the mildness of fibrosarcoma by inhibiting autophagy. Sci Rep. 2019, 9(1), 15042 

24. Park PJ, Rha CS, Kim ST. Theaflavin-enriched fraction stimulates adipogenesis in human subcutaneous fat cells. Int J Mol Sci. 2019, 20(8), pii: E2034. 

25. Kim ST, Park T. Acute and Chronic Effects of cocaine on cardiovascular health. Int J Mol Sci. 2019, 20(3), pii: E584. 

26. Do YS, Cho KH, Kim HC, Kwon JY, Kim ST, Park SY, Kim YH, Kim JE, Park YJ, Maeng HJ, Jang DJ. Preparation of silica microparticles as volatile material carrier and their sustained-release property. J Nanosci Nanotechnol. 2019, 19(2), 1188-1191. 

27. Kim HI, Jee JP, Kim ST, Kang D, Kim YC, Kim C, Park SY, Lee HM, Cho KH, Kim DY, Choi SU, Jang DJ. Preparation and characterization of celecoxib nanosuspension using bead milling. J Nanosci Nanotechnol. 2019, 19(2), 1184-1187. 

28. Cho KH, Jee J, Yang D, Kim ST, Kang D, Kim D, Sim T, Park SY, Kim K, Jang D. Improved dissolution and oral bioavailability of celecoxib by a dry elixir system. J. Nanosci Nanotechnol, 2018, 18(2), 1482-1486. 

29. Bin BH, Seo J, Kim ST. Function, structure, and transport aspects of ZIP and ZnT Zinc transporters in immune cells. J Immunol Res. 2018, 2018, 9365747. 

30. Kim Y, Kim ST, Jee J, Kim D, Kang D, Kim K, Park SY, Sim T, Cho KH, Jang D. Removing control of cyclodextrin-drug complexes using high affinity molecule, J Nanosci Nanotechnol, 2018, 18(2), 898-901. 

31. Elci SG, Yesilbag Tonga G, Yan B, Kim ST, Kim CS, Jiang Y, Saha K, Moyano DF, Marsico ALM, Rotello VM, Vachet RW. Dual-mode mass spectrometric imaging for determination of in vivo stability of nanoparticle monolayers. ACS Nano, 2017, 11(7), 7424-7430. 

32. Le NDB, Yesilbag Tonga G, Mout R, Kim ST, Wille ME, Rana S, Dunphy KA, Jerry DJ, Yazdani M, Ramanathan R, Rotello CM, Rotello VM. Cancer cell discrimination using host-guest "doubled" arrays. J Am Chem Soc 2017, 139(23), 8008-8012. 

33.Lee K, Choi GS, Kim TW, Kwan Cho KH, Kang D, Kim ST, Jang D. Modeling and optimization of dough properties using response surface design. Food Engineer Prog, 2017, 21(2), 132-137.

34. Bin BH, Kim ST, Bhin J, Lee TR, Cho EG. Synergistic effect of maltose for enhancing anti-melanogenic activity of acarbose. Arch Dermatol Res 2016, 309(3), 217-223. 

35. Hou S, Tang R, Kim ST, Jiang Z, Vachet R, Rotello VM. Quantitative mass spectrometric differentiation of cell surface-bound and internalized nanoparticles. ACS Nano. 2016, 10(7), 6731-6736. 

36. Elci SG, Jiang Y, Yan B, Kim ST, Saha K, Moyamo DF, Yesilbag Tonga G, Jackson LC, Rotello VM, Vachet RW. Surface charge controls the suborgan biodistributions of gold nanoparticles. ACS Nano. 2016, 10(5), 5536-5542. 

37. Bin BH, Kim ST, Bhin J, Lee TR, Cho EG. The development of sugar-based anti-melanogenic agents. Int J Mol Sci. 2016, 17(4), 583.

38. Kim ST, Jeong Y, Jiang Y, Duncan B, Kim CS, Saha K, Yeh Y, Yan B, Tang R, Hou S, Kim C, Park M, Rotello VM. Nanoparticle-dendrimer hybrid nanocapsules for therapeutic delivery. Nanomedicine. 2016, 11(12), 1571-1578. 

39. Elci SG, Yan B, Kim ST, Saha K, Jiang Y, Klemmer GA, Moyano DF, Tonga GY, Rotello VM, Vachet RW. Quantitative imaging of 2 nm monolayer-protected gold nanoparticle distributions in tissues using laser ablation inductively-coupled plasma mass spectrometry (LA-ICP-MS). Analyst. 2016, 141(8), 2418-2425. 

40. Bin BH, Kim D, Kim N, Choi E, Bhin J, Kim ST, Gho YS, Lee A, Lee TR, Cho EG. Fibronectin-containing extracellular vesicles protect melanocytes against ultraviolet radiation-induced cytotoxicity. J Invest Dermatol. 2016, 136(5), 957-966.

41. Saha K, Rahimi M, Yazdani M, Kim ST, Moyano DF, Hou S, Das R, Mout R, Rezaee F, Mahmoudi M, Rotello VM. Regulation of macrophage recognition through the interplay of nanoparticle surface functionality and protein corona. ACS Nano. 2016, 10(4), 4421-4430. 

42. Tonga GY, Jeong Y, Duncan B, Mizuhara T, Mout R, Das R, Kim ST, Yeh YC, Yan B, Hou S, Rotello VM. Supramolcular regulation of bioorthogonal catalysis in cells using nanoparticle-embedded transition metal catalysts. Nat Chem. 2015, 7(7), 597-603. 

43. Duncan B, Li X, Landis RF, Kim ST, Gupta A, Wang LS, Ramanathan R, Tang R, Boerth JA, Rotello VM. Nanoparticle-stabilized capsules for the treatment of bacterial biofilms. ACS Nano. 2015, 9(8), 7775-7782. 

44. Kim C, Tonga GY, Yan B, Kim CS, Kim ST, Park MH, Zhu Z, Duncan B, Creran B, Rotello VM. Regulating exocytosis of nanoparticles via host-guest chemistry. Org Biomol Chem. 2015, 13(8), 2474-2479. 

45. Ding Y, Jiang Z, Saha K, Kim CS, Kim ST, Landis RF, Rotello VM. Gold nanoparticles for nucleic acid delivery. Mol Ther. 2014 22(6), 1075-1083. 

46. Kim ST, Yeh YC, Tang R, Yan B, Rotello VM. Insulin-Based Regulation of glucose-functionalized nanoparticle uptake in muscle cells. J Mater Chem B Mater Biol Med. 2014. (doi: 10.1039/C4TB00608A.) 

47. Kim ST, Park MH, Rana S, Solfiell D, Jeong Y, Duncan B, Yan B, Aksoy B, Rotello VM. Replenishable dendrimer-nanoparticle hybrid membranes for sustained release of therapeutics. Nanoscale. 2013, 5(17), 7805-7808. 

48. Kim ST, Saha K, Kim C, Rotello VM. The role of surface functionality in determining nanoparticle cytotoxicity. Acc Chem Res. 2013, 46(3), 681-691. 

49. Kim ST, Saha K, Yan B, Miranda OR, Alfonso FS, Shlosman D, Rotello VM. Surface functionality of nanoparticles determines cellular uptake mechanisms in mammalian cells. Small. 2013, 9(2), 300-305.

50. Yan B, Kim ST, Kim CS, Saha K, Moyano DF, Xing Y, Jiang Y, Roberts AL, Alfonso FS, Rotello VM, Vachet RW. Multiplexed imaging of nanoparticles in tissues using laser desorption/ionization mass spectrometry. J Am Chem Soc. 2013 135(34):12564-12567. 

51. Jang D, Kim ST, Oh E, Ban E. Enhanced oral bioavailability and controlled release of dutasteride by a novel dry elixir. Biomed Mater Eng. 2013, 23, S591-599. 

52. Jang D, Kim ST, Lee K, Oh E. Improved bioavailability and anti-asthmatic efficacy of poorly soluble curcumin-solid dispersion granules obtained using fluid bed granulation. Biomed Mater Eng. 2013 23, S433-449. 

53. Jang D, Kim ST, Oh E, Lee K. Enhanced oral bioavailability and anti-asthmatic efficacy of curcumin using redispersible dry emulsion. Biomed Mater Eng. 2013 23, S957-970. 

54. Kim ST, Chompoosor A, Yeh YC, Agasti SS, Solfiell DJ, Rotello VM. Dendronized gold nanoparticles for siRNA delivery. Small. 2012, 8(21), 3253-3256.

55. Ban E, Shin H, Kim ST, Kim CK. Determination of 3alpha-hydroxytibolone by LC/MS/MS with electrospray ionization method and its application to bioequivalence study in human plasma. J Pharm Invest. 2012, 42, 353-360. 

56. Hong YJ, Kim N, Lee K, Sonn CH, Lee JE, Kim ST, Baeg IH, Lee KM. Korean red ginseng (Panax ginseng) ameliorates type 1 diabetes and restores immune cell compartments. J Ethnopharmacol. 2012, 144(2), 225-233. 

57. Min JH, Kim ST, Lee JS, Kim K, Wu JH, Jeong J, Song A, Lee KM, Kim YK. Labelling of macrophage cell using biocompatible magnetic nanoparticles. J Appl Phys. 2011, 109(7), 07B309. 

58. Kim TJ, Kim N, Kang HJ, Kim EO, Kim ST, Ahn HS, Bluestone JA, Lee KM. FK506 causes cellular and functional defects in human natural killer cells. J Leukoc Biol 2010, 88(6), 1089-1097. 

59. Hong SJ, Kim ST, Kim TJ, Kim EO, Ahn CM, Park JH, Kim JS, Lee KM, Lim DS. Arterioscler Thromb Vasc Biol 2010, 30(12), 2655-2665. 

60. Kim ST, Kim DJ, Kim TJ, Seo DW, Kim TH, Lee SY, Kim K, Lee KM, Lee SK. Novel streptavidine-functionalized silicon nanowire arrays for CD4+ T lymphocyte separation. Nano Lett. 2010, 10(8), 2877-2883. 

61. Park TH, Kim ST, Park JS, Choi HG, Kim HT, Kim CK. Effect of zinc oxide on the rheological and mucoadhesive properties of poloxamer 407-based mucoadhesive thermosensitive gel. Drug Dev Ind Pharm. 2010, 36(12), 1436-1443. 

62. Kim EO, Kim TJ, Kim N, Kim ST, Kumar V, Lee KM. Homotypic cell to cell cross-talk among human natural killer cells reveals differential and overlapping roles 2B4 and CD2. J Biol Chem. 2010, 285(53), 41755-41764. 

63. Kim ST, Park J, Kim HT, Kim CK. Simple determination of erdosteine in human plasma using high performance liquid chromatography. J Liq Chromatogr Rel Technol 2010, 33(13), 1319-1327.

Patent

1. Composition comprising lactic acid bacteria derived extracellular vesicles for preventing hair loss or promoting hair growth. Inventor: Kim ST, Lee YH, Shin SH, Hwang K, Cho EG, Lee TR. (KP application 1020150137862)

2. Ant-inflammatory composition comprising extracellular vesicles derived from yeast. Inventor: Kim ST, Cho EG, Lee TR, Kim SR, Hong KH, Gho YS. (KP application)

3. Composition for promoting angiogenic activity comprising exosome-mimetic nanovesicles derived from adult stem cells. Inventor: Kim ST, Cho EG, Bin BH, Lee TR, Kim SR, Hong KH, Gho YS (KP application)

4. Composition for skin whitening and method for screening the skin whitening materials. Inventor: Bin BH, Cho EG, Choi E, Kim ST, Choi SY, Lee TR. (KP application 1020150093049)　

5. Cell separation chip using silicon nanowire. Inventors: Lee SK, Kim DJ, Lee SY, Lee KM, Kim ST. Korea Patent number: KP 1020100029381

Book

1.T. A. Brown 생화학 포커스 (공역) ㈜ 바이오사이언스출판

(박사) Illinois Inst.of Tech. 화학공학과

· Rice University, Institute of Bioscience and  Bioengineering, 

  Post-Doctor (1991-1993) 

· 인제대학교 제약공학과 (1994-현재) 

· 한국제약공학회 학술이사, 총무이사(2005 ~ 2011) 

· 한국 화학공학회 공업화학부문 위원장(2011-12) 

· 2016년 한국화학공학회 국문지 공로상 수상

· 한국제약공학회장(2019.05.~) 

· 기능성 스킨케어 화장품

· 색조화장품

· 피부질환치료제 개발

· 제약통계

· GMP 

· GMP실험

· 화장품학

· 피부과학(대학원)

· 화장품소재(대학원)

논문

1.심*은, 노*영, 김*민, 김*연, 남*석, 김*욱, 쉘락/젤라틴을 함유한 저자극·친환경 매니큐어 개발, Korean Chem.Eng.Res.. 57,22,2019

2.한*균, 노*영, 심*은, 장*하, 박*호, 최*선, 김동욱, 괭이밥과 추출물의 기능성화장품소재로서의 특성, Korean Chem. Eng. Res..56,309,2018

3.노*영, 조*현, 양*욱, 한*균, 김*홍, 김*욱, 황벽나무, 두충나무 등을 포함한 천연 추출물의 항균력 및 안전성, Korean Chem. Eng. Res., 54(6), 762, 2016

4.김*우, 신*진, 황*비, 이*은, 정*리, 김*욱, 여주 열매 추출물의 기능성화장품 소재 특성, Korean Chem. Eng. Res., 53, 289, 2015

5.황*비, 신*진, 정*리, 노*영, 김*성, 김*홍, 김*욱, 녹차, 삼백초, 귀룽나무 등을 포함한 식물성 추출물의 샴푸로서의 특성 Korean Chem. Eng. Res., 53, 663, 2015

6.Danbi Hwang, Hyunwoo Kim, Hyejin Shin, Donguk Kim, Cosmetic effects of Prunus padus bark extract, Korean J. of Chemical Engineering, 31 (12), 2280, 2014

7.신*진,정*리, 황*비, 김*욱, 꾸지뽕나무 뿌리 열수추출물로부터 미백 및 주름개선 화장품소재의 개발, Korean Chem. Eng. Res., 52, 1, 2014

저서

1. 소재를 중심으로 한 화장품학, 자유아카데미, 2020.

2. Excel을 활용한 제약통계학, 자유아카데미, 2020.

3. 제약공학 개론, 4판, 자유아카데미, 2020.

특허

1. 꾸지뽕 추출물을 유효성분으로 포함하는 화장료 조성물 및 그의 제조 방법, 특허등록 10-1577246호

2. 연꽃, 연잎, 연줄기, 연근, 연자육의 열수 추출 방법 및 그에 의하여 제조된 추출물을 유효성분으로 하는 주름개선 효과를 가지는 화장료 조성물, 특허 등록 10-1229045호

3.알로에 추출물을 포함하는 매니큐어 조성물, 특허등록 10-1777408호

4.보름달 물해파리의 추출방법 및 이에 의하여 추출된 보름달 물해파리 추출물을 함유하는 수면팩 조성물, 특허등록 10-1927080호

5. 쉘락을 이용한 손발톱용 저자극 매니큐어 조성물 및 그의 제조방법, 특허등록 1021062120000

6. 매니큐어 용기, 특허 등록  1020162590000

(박사)울산과학기술원 생명과학과

· Ph.D., Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST)

· Postdoctoral fellow, Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST)

· Visiting Scholar, Department of Bioengineering, University of California, Berkeley (UC Berkeley)

· Postdoctoral fellow, Department of Bioengineering, University of California, Berkeley (UC Berkeley)

· Targeted Drug Delivery System, Intracellular delivery of therapeutics, Protein-based Theragnostic Systems

· Gene therapeutics

· Nanobiotechnology and Protein engineering

· Biosensing & Imaging

· 병원미생물학 (Microorganisms)

· 생물의약품학 (Biopharmaceuticals)

· 의약품분석학 (Pharmaceutical analysis)

1. Li, J., Tuma, J., Han, H., Kim, H., Wilson, R., Lee, H.Y. & Murthy, N., The Coiled-Coil Forming Peptide (KVSALKE)5 is A Cell Penetrating Peptide that Enhances the Intracellular Delivery of Proteins. Advanced Healthcare Materials, 2021, p.2102118

2. Choi, H., Eom, S., Kim, H., Bae, Y., Jung, H. S., and Kang, S., Load & Display: Engineering Encapsulin as a Modular Nanoplatform for Protein-cargo Encapsulation and Protein-ligand Decoration Using Split Intein and SpyTag/SpyCatcher. Biomacromolecules, 2021, DOI:10.1021/acs.biomac.1c00481

3. Kim, H.*, Jin, S.*, Choi, H., Kang, M., Park, SG., Jun, H., Cho, H., and Kang, S., Target-switchable Gd(III)-DOTA/protein cage nanoparticle conjugates with multiple targeting affibody molecules as target selective T1 contrast agents for high-field MRI. Journal of Controlled release, 2021, 335, 269-280.

4. Kim, H., Choi, H., Bae, Y., and Kang, S., Development of Target-Tunable P22 VLP-Based Delivery Nanoplatforms Using Bacterial Superglue. Biotechnol. Bioeng., 2019, 116, 2843-2851. *Editor's Choice Article.

5. Oh, J. Y*, Kim, H.*, Palanikumar, L.*, Go, E. M., Jana, B., Park, S. A., Kim, H. Y., Kim, K., Seo, J. K., Kwak, S. K., Kim, C., Kang, S., and Ryu, J-H., Cloaking Nanoparticles with Protein Corona Shield for Targeted Drug Delivery. Nat. Comm., 2018, 9, 4548.

6. Kim, H.*, Kang, Y. J.*, Min, J., Choi, H. and Kang, S. Development of an Antibody-binding Modular Nanoplatform for Antibody-guided Targeted Cell Imaging and Delivery. RSC Adv., 2016, 6, 19208-19213. 

7. Choi, B., Kim, H., Choi, H., and Kang, S., Protein Cage Nanoparticles as Delivery Nanoplatforms. Adv. Exp. Med. Biol. 2018, 1064, 27-43.

8. Choi, H., Choi, B., Kim, H., Kim, G. J., Kim, H., Jung, H. S., and Kang, S., Fabrication of Nano-reaction Clusters with Dual-functionalized Protein Cage Nano-building Blocks. Small, 2018, 14, 1801488.

9. Bae, Y., Kim, G.J., Kim, H., Park, S.G., Jung, H.S., and Kang, S., Engineering Tunable Dual Functional Protein Cage Nanoparticles using Bacterial Superglue. Biomacromolecules, 2018, 19, 2896-2904.

10. Moon, H., Bae, Y., Kim, H. and Kang, S., Plug-and-Playable Fluorescent Cell Imaging Modular Toolkits Using the Bacterial Superglue, SpyTag/SpyCatcher. Chem. Comm., 2016, 52, 14051-14054.

11. Min, J.*, Song, E. K.*, Kim, H., Kim, K. T., Park, T. J. and Kang, S., A Recombinant Secondary Antibody Mimic as a Target-specific Signal Amplifier and an Antibody Immobilizer in Immunoassays. Sci. Rep. 2016, 6, 24159.

12. Song, Y. K.*, Kang, Y. J.*, Jung, H., Kim, H., Kang, S. and Cho, H. J., Lumazine Synthase Protein Nanoparticle-Gd(III)-DOTA Conjugate as a T1 contrast agent for high-field MRI. Sci. Rep. 2015, 5, 15656.

13. Moon, H., Lee, J., Kim, H., Heo, S., Min, J. and Kang, S., Genetically Engineering Encapsulin Protein Cage Nanoparticle as a SCC-7 Cell Targeting Optical Nanoprobe. Biomater. Res., 2014, 18,21.

1. Ryu, J-H., Oh, J. Y., Kim, H., Kim, C., Kang, S., “Fusion protein comprising glutathione-S-transferase and protein binding to target cell or target protein and uses thereof”, Korean Patent No. 1021122690000 (2020)

2. Ryu, J-H., Oh, J. Y., Kim, H., Kim, C., Kang, S., “HER2-GST-CPT complex, and pharmaceutical composition for preventing or treating cancer comprising the same”, Korean Patent No. 1021144470000 (2020)

3. Ryu, J-H., Oh, J. Y., Kim, H., Kim, C., Kang, S., “EGFR-GST-drug complex, and pharmaceutical composition for preventing or treating cancer comprising the same”, Korean Patent No. 1021144450000 (2020)'

- 숙명여자대학교 약학대학 약학사

- 숙명여자대학교 약학대학 약학석사 (약제학)

- 성균관대학교 약학대학 약학박사 (사회약학)

- 제일약품, 임상팀

- GSK, Medical

- IQVIA, Management consulting

- IQVIA, Real world solution

- Outcomes research using healthcare big data (national claims, hospital EMR)

- Development of secondary database evidence network

- Longitudinal data analysis, including patient journey and treatment pathway analytics

- Clinical research

- Regulatory science

- Healthcare big data

논문

1.    Kim KP, Kim KM, Ryoo BY, Choi WM, Cha WC, Kang MR, Sinne DH, Goh MJ, Kim DY, Lee MJ, Lim SB, Kim DK, Baek KD, Kim JH, Choi EJ, Lee DI, Kim JA, Kim. Prognostic Efficacy of the Albumin-Bilirubin Score and Treatment Outcomes in Hepatocellular Carcinoma: A Large-Scale, Multi-Center Real-World Database Study. Liver Cancer, 2024; doi: 10.1159/000539724 

2.    Kim MY, Kim JA, Lee YE, Lee SK. Treatment compliance, treatment patterns, and healthcare utilization in epilepsy patients with first add-on antiepileptic drugs: A nationwide cohort study. Heliyon, 2024; 10(6)e27770. doi:10.1016/j.heliyon.2024.e27770.

3.    Jung HA, Lee DH, Lim SM, Yu H, Yoon S, Kim D, Kim KP, Jeong H, Doh H, Lim S, Kim J, Zhao X, Horsburgh D, Patel D, Kim JA, Toh KC. Epidemiology and Outcomes of Non-Small Cell Lung Cancer in South Korea. JAMA Netw Open. 2024;7(2):e2355331. doi:10.1001/jamanetworkopen.2023.55331.

4.    Lee SH, Park Y, Choi CB, Kim YG, Kim JA, Cha HS. Usability and understandability of a web-based medical communication aid for patients with ankylosing spondylitis in South Korea: A mixed-methods study. Medicine (Baltimore). 2023;102(14):e33430. doi:10.1097/MD.0000000000033430

5.    Kim J, Kim MY, Kim JA, Lee Y. Factors affecting preventive behaviors of Alzheimer's disease in family members of patients with Alzheimer's disease. Medicine (Baltimore). 2022;101(42):e31136. doi:10.1097/MD.0000000000031136

6.    Lee JW, Kim JA, Kim MY, Lee SK. Evaluation of persistence and healthcare utilization in patients treated with anti-seizure medications as add-on therapy: A nationwide cohort study in South Korea [published online ahead of print, 2021 Dec 10]. Epilepsy Behav. 2021;126:108459. doi:10.1016/j.yebeh.2021.108459

7.    Cho YT, Lee JY, Shim DY, Park SJ, Rhee HE, Sung HG, Kim HJ, Choi NK, Song HJ, Kim JA, Park SM, Shin JY. Comparison of Postmarket Surveillance Strategies of Implantable Medical Devices in the United States, European Union, and South Korea. J Pharmacoepidemiology and risk management 2021;13:45-54

8.    EOh KJ, Nam EJ, Kim SW, Shin M, Kim SJ, Kim JA, Kim YT. Nationwide Comparison of Surgical and Oncologic Outcomes in Endometrial Cancer Patients Undergoing Robotic, Laparoscopic, and Open Surgery: A Population-Based Cohort Study. Cancer Res Treat. 2021;53(2):549-557. doi:10.4143/crt.2020.802

9.    Lee SR, Choi EK, Kim JH, Kim JA, Kwon TY, Lee YE, Oh S. Comparative clinical outcomes of dronedarone and sotalol in Asian patients with atrial fibrillation: a nationwide cohort study. Sci Rep. 2020;10(1):16102. doi:10.1038/s41598-020-73115-y

포스터

1.    KP Kim, KM Kim, WC Cha, MR Kang, DH Shinn, DY Kim, MJ Lee, SB Lim, JH Kim, EJ Choi, JA Kim, Cindy TK Lim, NJ Kleinman, GY Kwon, JH Park, MY Kim, KH Kim. Establishing a Large-Scale, Multi-Center Hepatocellular Carcinoma Database in South Korea for Rapid Real-World Evidence Generation. ASCO 2023.

2.    CH Bang, YS Kim, JH An, ES Jung, JY Ahn, JA Kim, CJ Park. Prevalence and incidence of psoriatic arthritis among patients with psoriasis and risk factors for psoriatic arthritis in Republic of Korea: A nationwide database study. ISDS 2023.

3.    KC Toh, XH Zhao, JH Kim, G Stratton, HW Lin, DH Lee, SK Yoon, YF Fang, KC Chang, R. G Stirling, J Zalcberg, HA Jung, HY Yu, SM Lim, SB Lim, KP Chou, JA Kim, D Patel, NJ Kleinman. EXPLORE-LC: A multi-site real-world evidence research platform for non-small cell lung cancer in Asia-Pacific. ESMO ASIA 2022.

4.    SK Yoon, SM Lim, HA Jung, KP Kim, DK Kim, HH Jeong, SB Lim, JA Kim, JH Kim, D Patel, XH Zhao, D Horsburgh, DY Yu, JH Kim, SY Kim, DH Lee. Clinical Characteristics, Treatment Patterns and Outcomes of EGFR Exon 20 insertion and other EGFR Mutations in Korean Advanced NSCLC Patients. ELCC 2022.

5.    HA Jung, DH Lee, SM Lim, SK Yoon, DK Kim, KP Kim, HH Jeong, HW Do, SB Lim, JH Kim, KC Toh, D Patel, JA Kim, D Horsburgh, KC Park. Initial and palliative treatment patterns for non-small cell lung cancer (NSCLC) in South Korea: A multi-EMR analysis from the EXPLORE-LC research network. AACR-KCA Joint Conference 2021.

6.    JW Lee, JA Kim, MY Kim, SK Lee. Evaluation of persistence and healthcare utilization in Korean patients treated with anti-epileptic drug first add-on therapy. AOEC 2021.

7.    DaYo, Park SJ, Rhee HE, Sung HG, Kim HJ, Choi NK, Song HJ, Kim JA, Park Sm, Shin JY. Comparison of Postmarket Surveillance Strategies of Implantable Medical Devices in the United States, European Union, and South Korea. J Pharmacoepidemiol Risk Manage. 2021;13(2):45-54.

8.    D Horsburgh, SS Song, JH Kim, KC Toh, J Ng, G Stratton, DaH Lee, SK Yoon, KC Park, HA Jun, SM Lim, DK Kim, R Stirling, JA Kim, D Patel. EXPLORE-LC: Uniting Existing Real-World Data Sources to Create a Novel Asia-Pacific Wide Research Platform for Non-Small Cell Lung Cancer (NSCLC). WCLC 2020.

9.    D Horsburgh, D Patel, SS Song, J Ng, JA Kim. JH Kim. Explore-LC: Uniting Existing Real-World DATA Sources to Create a NOVEL ASIA-Pacific Wide Research Platform for NON-SMALL CELL LUNG Cancer. ISPOR Asia Pacific 2020.

10.    MS Kim, YE Oh, DI Lee, V Casey, C Anger, JA Kim. The role of different specialties in the management of non-small cell lung cancer: insights from a real-world study. ISPOR Asia Pacific 2020.

11.    MK Shin, Stella JH Kim, HJ Kang, KJ Eoh, NH Song, JA Kim, YT Kim. An analysis of surgical trends in hysterectomy for endometrial cancer in Korea using the national health insurance and services (NHIS) claims database. ISPOR US 2020.

12.    MK Shin, Stella JH Kim, HJ Kang, KJ Eoh, NH Song, JA Kim, YT Kim. A cost analysis of open, laparoscopic and robot-assisted hysterectomy for Endometrial Cancer in Korea. ISPOR Asia Pacific 2020.

13.    Stella JH Kim, HJ Kang, MK Shin, KJ Eoh, NH Song, JA Kim, YT Kim. Inequality of access to minimally invasive hysterectomy for patients with endometrial cancer in South Korea. ISPOR Asia Pacific 2020.

(박사) 강원대학교 화학과

· 강원대학교 기초과학연구소 전임연구원(2013.11.-2014.08.)

· 유한양행 중앙연구소 선임연구원(2014.08.-2016.09.)

· 인제대학교 제약공학과(2016.09.-현재)

· McMurry 일반화학 8판 번역 (자유아카데미)

· 전이금속 촉매 유기 반응

· 유기합성방법론

· 공정개발

· 유기화학I, 유기화학II, 유기화학실험 

· 일반화학I, 일반화학II

· 원료의약품 개발

논문

1. Park, Y.; Kang, D.; Jeon, W. H.; Ryu, T.; Lee, P. H.* Synthesis of Ethyl Arylpropiolates through Palladium-Catalyzed Cross-Coupling Reactions of Aryl Iodides with In Situ Generated Lithium Tetra(ethoxycarbonylethynyl)indates, Synthesis 2014, 46, 2305-2311.

2. Shin, S.; Kang, D.; Jeon, W. H.; Lee, P. H.* Synthesis of Ethoxy Dibezooxaphosphorin Oxides through Palladium-Catalyzed C(sp2)-H Activation/C-O Formation, Beilstein J. Org. Chem. 2014, 10, 1220-1227.

3. Kim, J.; Kang, D.; Yoo, E. J.; Lee, P. H.* Palladium-Catalyzed Decarboxylative C-H Alkynylation of Benzoxazoles with α,β-Ynoic Acids, Eur. J. Org. Chem. 2013, 7902-7906.

4. Kang, D.; Cho. J.; Lee, P. H.* Palladium-Catalyzed Direct C-3 Oxidative Alkenylation of Phosphachromones, Chem. Commun. 2013, 49, 10501-10503.

5. Mo, J.; Kang, D.; Eom, D.; Kim, S. H.; Lee, P. H.* Gold-Catalyzed Sequential Alkyne Activation for the Synthesis of 4,6-Disubstituted Phosphorus 2-Pyrones, Org. Lett. 2013, 15, 26-29.

6. Kang, D.; Kim, J.; Oh, S.; Lee, P. H.* Synthesis of Naphthalenes via Platinum-Catalyzed Hydroarylation of Aryl Enynes, Org. Lett. 2012, 14, 5636-5639.

7. Kang, D.; Park, S.; Ryu, T.; Lee, P. H.* Gold-Catalyzed Hydrosilyloxylation Driving Tandem Aldol and Mannich Reactions, Org. Lett. 2012, 14, 3912-3915.

8. Kim. S.; Kang, D.; Lee, C.-H.; Lee, P. H.* Synthesis of Substituted Coumarins via Brønsted Acid Mediated Condensation of Allenes with Substituted Phenols or Anisoles, J. Org. Chem. 2012, 77, 6530-6537