- (학사) 서울대학교 농생물학과

- (석사) 한국과학기술원(KAIST) 생물공학과

- (박사) 한국과학기술원(KAIST) 생물공학과

- 미국 위스콘신대학교 의과대학 박사 후 연구원(1991-1993) 

- 인제대학교 생명과학부교수(1993-2017),

- 인제대학교 바이오테크놀로지학부 교수(2017-2020 현재)

- 미국 위스콘신대학교 세균학과 객원교수(1999-2001)

- 보건복지부 장관 표창 (2010)

-(주)제노포커스. 세균 고발현시스템 기술이전

- 미생물에서 효소 대량발현기술

- 미생물 생명공학

-바이오테크놀로지 입문

- 미생물학, II

- 바이오테크놀로지실험Ⅱ

- 바이오의약품세미나

- 유전공학 및 실험

- 2007. Interaction Proteome Analysis of Xanthomonas Hrp Proteins.  J. Microbiol. Biotechnol. 17(2) 359-363.

- 2006. Proteome Analysis of Bacillus subtilis When Overproducing Secretory Protein.  J. Microbiol. Biotechnol. 16(3) 368-373, (2007) 

연세대학교 생화학과, 학사

포항공과대학교, 박사

포항공대 생명과학과 박사 후 연구원

University of Virginia, Research Associate

Yale University, Associate Research Scientist

인제대학교 바이오테크놀로지 학부, 조교수

인제대학교 바이오테크놀로지 학부 조교수 2020.4-

NAVBO (North America Vascular Biology Organization) member

AHA (American Heart Association) member

한국지질동맥경화학회 회원

▪ Vascular inflammation and atherosclerosis 

▪ Extracellular Matrix (ECM) remodeling

▪ ECM/integrin-dependent endothelial signaling and phenotype

▪ Fluid shear stress-dependent endothelial mechanotransduction 

생화학I, II

생물정보학

신경생물학

바이오의약품 품질관리

1. Sanguk Yun, Rui Hu, Melanie E. Schwaemmle, Alexander N. Scherer, Zhenwu Zhuang, Anthony J. Koleske, David C. Pallas, and Martin A. Schwartz (2019) Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis. Journal of Clinical Investigation 130. pii: 127692

2. Sanguk Yun, Madhusudhan Budatha, James E. Dahlman, Brian G. Coon, Ryan T. Cameron, Robert Langer, Daniel G. Anderson, George Baillie and Martin A. Schwartz (2016) Interaction between integrin a5 and PDE4D regulates endothelial inflammatory signaling. Nature Cell Biology 18, 1043–1053

3. Sanguk Yun*, Nicolas Baeyens*, Chirosree Bandyopadhyay*, Brian G. Coon* and Martin Schwartz (2016) Endothelial fluid shear stress sensing in vascular health and disease. Journal of Clinical Investigation 126(3), 821-828 *Equal contribution.

- (학사) 서울학교 미생물학과

- (석사) 서울대학교 미생물학과

- (박사) 영남대학교 생물학과

- 육군제3사관학교 생물학 강사(1981～1983)

- University of Wyming 연구원 (1988～1992)

- 서울대학교 분자미생물센터연구원 (1992-1993)

- 인제대학교 생명공학, 생명과학부 교수 (1993~ 2017)

- 인제대학교 바이오테크놀로지학부 교수(2017~현재)

- 조류독감 제어 기술개발

- 스테로이드 호르몬 수용체 신호전달

- Gene targeting에 의한 질병 생쥐 모델 개발

- 생리학입문

- 생명공학기초실험

- 바이오테크놀로지실험Ⅰ

- 분자세포생물학

- 질환분자생물학

- 유전자조작 및 실습

- 유전체학

- Orientation of follicle-stimulating hormone (FSH) subunits complexed with the FSH receptor. Beta subunit toward the N terminus of exodomain and alpha subunit to exoloop 3 J. Biol. Chem. 278(48):47868-76 2003

- An upstream initiator-like element suppresses transcription of the rat luteinizing hormone receptor gene. Mol. Endocrinol. 19(5): 1318-1328 2005

- Decay-Accelerating Factor (DAF) in the Periovulatory Rat Ovary. J. Endocrinol: 186:303-313 2005

- Endotheiln-2 in Ovarian Follicle Rupture. Endocrinology

 474:1770-1779 2006

- Kalirin is under-expressed in Alzheimer's Disease Hippocampus. J. Alzheimer's disease 11: 385-397 2007

- Glucocorticoids modulate NF-kB-dependent gene expressionby up-regulating FKBP51 expression in NDV-infected chickens. Mol. Cell. Endocrinol. 278:7-17 2007

- Pituitary gonadotroph estrogen receptor alpha (ER{alpha}) is necessary for fertility in females. Endocrinol. 149: 20-27 2008

- Role of hypoxia in the regulation of periovulatory EDN2 expression in the mouse. Can J Physiol Pharmacol. 2008 ;86:310-9.2008

- Generation of Cyp17iCre transgenic mice and their application to conditionally delete estrogen receptor alpha (Esr1) from the ovary and testis. Genesis 46:499-505 2008

- Theca-Specific Estrogen Receptor-α Knockout Mice Lose Fertility Prematurely. Endocrinology  150(8): 3855–3862. 2009

- Japanese encephalitis virus-based replicon RNAs/particles as an expression system for HIV-1 Pr55Gag that is capable of producing virus-like particles.  Virus Research 144: 298-305 2009

- An upstream initiator-like element suppresses transcription of the rat luteinizing hormone receptor gene. Mol. Endocrinol. 2005

- Decay-Accelerating Factor (DAF) in the Periovulatory Rat Ovary. J. Endocrinol: 2005

- Endotheiln-2 in Ovarian Follicle Rupture. Endocrinology 2006

- Kalirin is under-expressed in Alzheimer's Disease Hippocampus. J. Alzheimer's disease 2007

- Glucocorticoids modulate NF-kB-dependent gene expression by up-regulating FKBP51 expression in NDV-infected chickens. Mol. Cell. Endocrinol. 2007

- Pituitary gonadotroph estrogen receptor alpha (ER{alpha}) is necessary for fertility in females. Endocrinol.2007

- Role of hypoxia in the regulation of periovulatory EDN2 expression in the mouse. Can J Physiol Pharmacol. 2008 

- Generation of Cyp17iCre transgenic mice and their application to conditionally delete estrogen receptor alpha (Esr1) from the ovary and testis. Genesis 2008

- Japanese encephalitis virus-based replicon RNAs/particles as an expression system for HIV-1 Pr55Gag that is capable of producing virus-like particles.  Virus Research 2009

- 배양세포에서 Semi-quantitative RT-PCR에 의한 조류인플루엔자 H9N2의 전사활성 분석 최적 시기 결정 및 전사체 분석. 미생물학회지 2009

- (학사) 서울대학교 수의학과

- (석사) 서울대학교 수의미생물학

- (박사) Washington State University 수의미생물 및 면역학

- 서울대학교 수의과대학 연구교수

- Co-Director of Flow Cytometry Laboratory and Monoclonal Antibody Center, Washington State University

- 인제대학교 바이오테크놀로지학부 교수(2018~현재)

- Johne’s Disease Integrated Program (Member)

- Korean Society of Veterinary Science (Member)

- Korean Society of Food Hygiene and Safety (Editor)

- 감염미생물학

- 면역학

- 인수공통전염병

- 항생제 내성

- 생명과학

- 바이오테크놀로지실험Ⅱ

- 면역학

- 바이오테크놀로지실험Ⅲ

- 면역생명공학

- 바이오제품 디자인과 개발

- 감염성 질병 및 예방

- Simultaneous cognate epitope recognition by bovine CD4 and CD8 T cells is essential for primary expansion of antigen-specific cytotoxic T-cells following ex vivo stimulation with a candidate Mycobacterium avium subsp. paratuberculosis peptide vaccine.  Vaccine 2020.

 - relA is Achilles’ heel for mycobacterial pathogens as demonstrated with deletion mutants in Mycobacterium avium subsp. paratuberculosis and mycobacterium bovis bacillus Calmette-Guérin (BCG). Tuberculosis 2020

 - Livestock-associated methicillin-resistant Staphylococcus aureus in Korea: antimicrobial resistance and molecular characteristics of LA-MRSA strains isolated from pigs, pig farmers, and farm environment.  J Vet Sci 2020

 - A peptide-based vaccine for Mycobacterium avium subspecies paratuberculosis.  Vaccine 2019

 - Molecular characterization of a Korean porcine epidemic diarrhea virus strain NB1.  Can J Vet Res 2019

 - Capacity to Elicit Cytotoxic CD8 T Cell Activity Against Mycobacterium avium subsp. paratuberculosis Is Retained in a Vaccine Candidate 35 kDa Peptide Modified for Expression in Mammalian Cells.  Front Immunol 2019

 - Detection and Genetic Characterization of Porcine Epidemic Diarrhea Virus in South Korea.  International Journal of Applied Research in Veterinary Medicine 2019

 - A Mycobacterium avium subsp. paratuberculosis relA deletion mutant and a 35 kDa major membrane protein elicit development of cytotoxic T lymphocytes with ability to kill intracellular bacteria.  Vet Res 2018

 - Characterization of Methicillin-Resistant Staphylococcus pseudintermedius Isolated from Dogs in Veterinary Hospitals in Korea.  International Journal of Applied Research in Veterinary Medicine 2018

 - Mechanisms of quinolone resistance in Escherichia coli isolated from companion animals, pet-owners, and non-pet-owners.  J Vet Sci 2017.

 - Probable secondary transmission of antimicrobial-resistant Escherichia coli between people living with and without pets.  J Vet Med Sci 2017

 - Prevalence and Mechanism of Fluoroquinolone Resistance in Escherichia coli Isolated from Swine Feces in Korea.  J Food Prot 2017

 - Phenotypic and genotypic correlates of daptomycin-resistant methicillin-susceptible Staphylococcus aureus clinical isolates.  J Microbiol 2017

 - Isolation and characterization of antimicrobial-resistant Escherichia coli from national horse racetracks and private horse-riding courses in Korea.  J Vet Sci 2016

 - Characterization and use of new monoclonal antibodies to CD11c, CD14, and CD163 to analyze the phenotypic complexity of ruminant monocyte subsets.  Vet Immunol Immunopathol 2016

 - Antimicrobial resistance and virulence profiles of Enterococcus spp. isolated from horses in korea.  Comp Immunol Microbiol Infect Dis 2016

 - Effect of vaccination with a modified live porcine reproductive and respiratory syndrome virus vaccine on growth performance in fattening pigs under field conditions.  J Vet Med Sci 2016

 - Genotypic and Phenotypic Characterization of Methicillin-Resistant Staphylococcus aureus Isolated from Bovine Mastitic Milk in Korea.  J Food Protect 2016

 - Phenotype and Function of CD209+ Bovine Blood Dendritic Cells, Monocyte-Derived-Dendritic Cells and Monocyte-Derived Macrophages.  PLoS One 2016

 - Development and characterization of a monoclonal antibody specific for bovine CD209.  Vet Immunol Immunopathol 2015

 - Characterization and expression of monoclonal antibody-defined molecules on resting and activated bovine alphabeta, gammadelta T and NK cells.  Vet Immunol Immunopathol 2015

 - Deletion of relA abrogates the capacity of Mycobacterium avium paratuberculosis to establish an infection in calves.  Frontiers in cellular and infection microbiology 2014

 - Development of a novel DNA extraction method for identification and quantification of Mycobacterium avium subsp. paratuberculosis from tissue samples by real-time PCR.  Journal of microbiological methods 2014

 - Characterization of a Mycobacterium avium subsp. avium operon associated with virulence and drug detoxification.  BioMed research international 2014

- (학사) 연세대학교 생화학과

- (석사) 서울대학교 분자생물학과

- (박사) 서울대학교 생명과학부

- Stanford 의과대학 Post-doctoral fellow(2002～2007)

- 인제대학교 생명공학부, 생명과학부 교수(2007~2017)

- 인제대학교 바이오테크놀로지학부 교수(2017~현재)

- 한국생화학분자생물학회 뉴스레터 편집위원

- 세포학

- 발생학, 줄기세포

- 암 관련 분야

- 세포성장조절, 노화

- 생명공학기초실험

- 세포생물학

- 바이오테크놀로지기기Ⅰ

- 바이오테크놀로지기기Ⅱ

- 바이오테크놀로지실험Ⅲ

- 암생물학

- 바이오캡스톤디자인

- 세포신호전달

- Coenzyme Q10 ameliorates the quality of mouse oocytes during in vitro culture. Zygote. 2020

- 5’-UTR and ORF elements, as well as the 3’-UTR regulate the translation of Cyclin. Biochemical and Biophysical Research Communications. 2020 

- Inducement of a spontaneously wrinkled polydimethylsiloxane surface and its potential as a cell culture substrate.Colloids Surf B Biointerfaces. 2018

-  The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle. Scientific Reports. 2017

- Maternal mRNAs with distinct 3' UTRs define the temporal pattern of Ccnb1 synthesis during mouse oocyte meiotic maturation. Genes and Development.2017

- Comparative analysis of two murine CDC25B isoforms. Arch Biol Sci. 2017

- Oocyte Maturation Process of Zebrafish (Danio rerio), an Emerging Animal Model.  Journal of Life Science. 2015

- Overexpression of Clast4 Reduces Cell Proliferation. Journal of Life Science 2014

- Fabrication of Hydrophilic Poly (dimethylsiloxane) with Periodic Wrinkling Surface and Its application. The Transactions of the Korean Institute of Electrical Engineers. 2014.

- NIR is Degraded by the Anaphase-Promoting Complex–Proteasome Pathway. Arch. Biol. Sci. 2014 

- p104 binds to Rac1 and reduces its activity during myotube differentiation of C2C12 cell.  The Scientific World Journal, 2014. 

-  NIR IS A NUCLEOLAR RNA-BINDING PROTEIN THAT IS INVOLVED IN CELL PROLIFERATION. Arch. Biol. Sci. 2013

- Cardamonin Suppresses the Proliferation of Colon Cancer Cells by Promoting β-Catenin Degradation. Biol. Pharm. Bull. 2013

-  Post-transcriptional and post-translational regulation during mouse oocyte maturation. BMB Rep. 2011.

- Novel p104 protein regulates cell proliferation through PI3K inhibition and p27Kip1 expression. BMB Rep. 2010

- Wee1B, Myt1, and Cdc25 function in distinct compartments of the mouse oocyte to control meiotic resumption. J. Cell Biol. 2010 

-  The roles of amino and carboxyl domains in the mouse Wee1 kinases.  Journal of Life Science 2008

-  Protein kinase B/Akt phosphorylation of PDE3A and its role in oocyte maturation. The EMBO J. 2006 

-  New Pathways from PKA to the Cdc2/cyclin B Complex in Oocytes: Wee1B as a Potential PKA Substrate. Cell Cycle. 2006 

- Wee1B Is an Oocyte-Specific Kinase Involved in the Control of Meiotic Arrest in the Mouse. Curr Biol. 2005

-  Synapsin IIb interacts with the C-terminal SH2 and SH3 domains of PLCgamma1 and inhibits its enzymatic activity. Cell Biol Int. 2004 

-  Identification of p115 as a PLCgamma1-binding protein and the role of Src homology domains of PLCgamma1 in the vesicular transport. Biochem Biophys Res Commun. 2003